Transconal Unroofing of Anomalous Left Main Coronary Artery from Right Sinus With Transseptal Course

Anomalous aortic origin of the left coronary artery (AAOLCA) from the right coronary sinus is a rare condition. However, this disease process is clinically important as it carries an increased risk of sudden cardiac death in otherwise healthy young persons, when compared to anomalous right coronary arteries. Anatomically, after its origin from the right coronary sinus, the anomalous left main coronary artery takes one of four courses: 1. Front of PA; 2. Behind the Aorta; 3. Between PA and Aorta; 4. Trans-septal course. In this trans-septal variant, the left main coronary artery dives into the interventricular septum behind the right ventricular outflow tract, and emerges on the epicardial surface, on the lateral aspect of the pulmonary annulus, before bifurcating into the LAD and left circumflex coronary arteries. This variant can be surgically challenging to repair with conventionally techniques. Coronary artery bypass grafting has been advocated, but prove to be a sub-optimal solution due to early risk of failure from competitive flow. Recently, our group developed a novel transconal approach that has not been previous described, and that adequately addresses the pathophysiologic issues with this variant. This technique has been demonstrated to provide improved fractional flow reserve values compared to pre-operative values, addresses the underlying pathophysiology of this variant, and is a safe and effective alternative to conventional surgical solutions.

Reference

Najm HK, Ahmad M. Transconal Unroofing of Anomalous Left Main Coronary Artery From Right Sinus With Trans-septal Course. Ann Thorac Surg. 2019 Dec;108(6):e383-e386. doi: 10.1016/j.athoracsur.2019.04.021. Epub 2019 May 15. PMID: 31102634.